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Fungal PathonesPreferred ++Acceptable +Possibly effective ±
Aspergillus calidoustusAmphotericin B Formulations
Aspergillus calidoustusCaspofungin, Micafungin, or Anidulafungin
Aspergillus fumigatusVoriconazoleAmphotericin B Formulations Itraconazole
Aspergillus fumigatusIsavuconazolePosaconazole
Aspergillus fumigatusCaspofungin, Micafungin, or Anidulafungin
Aspergillus terreusVoriconazoleItraconazole
Aspergillus terreusIsavuconazolePosaconazole
Aspergillus terreusCaspofungin, Micafungin, or Anidulafungin
Blastomyces dermatitidisAmphotericin B Formulations Fluconazole
Blastomyces dermatitidisItraconazoleVoriconazole
Blastomyces dermatitidisPosaconazole
Blastomyces dermatitidisIsavuconazole
Candida albicansFluconazoleAmphotericin B Formulations
Candida albicansCaspofungin, Micafungin, or AnidulafunginItraconazole
Candida albicansVoriconazole
Candida albicansPosaconazole
Candida albicansIsavuconazole
Candida albicansFlucytosine
Candida aurisCaspofungin, Micafungin, or AnidulafunginPosaconazoleAmphotericin B Formulations
Candida aurisIsavuconazoleItraconazole
Candida aurisVoriconazole
Candida aurisFlucytosine
Candida glabrataAmphotericin B Formulations Itraconazole
Candida glabrataFlucytosineVoriconazole
Candida glabrataPosaconazole
Candida glabrataIsavuconazole
Candida glabrataCaspofungin, Micafungin, or Anidulafungin
Candida guilliermondiiAmphotericin B Formulations Fluconazole
Candida guilliermondiiItraconazoleCaspofungin, Micafungin, or Anidulafungin
Candida guilliermondiiVoriconazole
Candida guilliermondiiPosaconazole
Candida guilliermondiiIsavuconazole
Candida guilliermondiiFlucytosine
Candida kruseiCaspofungin, Micafungin, or AnidulafunginAmphotericin B Formulations
Candida kruseiVoriconazole
Candida kruseiPosaconazole
Candida kruseiIsavuconazole
Candida kruseiFlucytosine
Candida lusitaniaeFluconazoleItraconazole
Candida lusitaniaeVoriconazole
Candida lusitaniaePosaconazole
Candida lusitaniaeIsavuconazole
Candida lusitaniaeFlucytosine
Candida lusitaniaeCaspofungin, Micafungin, or Anidulafungin
Candida parapsilosisAmphotericin B Formulations Itraconazole
Candida parapsilosisFluconazoleVoriconazole
Candida parapsilosisPosaconazole
Candida parapsilosisIsavuconazole
Candida parapsilosisFlucytosine
Candida parapsilosisCaspofungin, Micafungin, or Anidulafungin
Candida tropicalisCaspofungin, Micafungin, or AnidulafunginAmphotericin B Formulations
Candida tropicalisFluconazole
Candida tropicalisItraconazole
Candida tropicalisVoriconazole
Candida tropicalisPosaconazole
Candida tropicalisIsavuconazole
Candida tropicalisFlucytosine
Coccidioides immitisAmphotericin B Formulations Itraconazole
Coccidioides immitisFluconazoleVoriconazole
Coccidioides immitisPosaconazoleIsavuconazole
Cryptococcus sppAmphotericin B Formulations Fluconazole
Cryptococcus sppFlucytosineItraconazole
Cryptococcus sppVoriconazole
Cryptococcus sppPosaconazole
Cryptococcus sppIsavuconazole
FusariumVoriconazolePosaconazoleAmphotericin B Formulations
FusariumIsavuconazole
Histoplasma capsulatumAmphotericin B Formulations Fluconazole
Histoplasma capsulatumItraconazoleVoriconazole
Histoplasma capsulatumPosaconazole
Histoplasma capsulatumIsavuconazole
Lomentospora(Scedosporium prolificans)Itraconazole
Lomentospora(Scedosporium prolificans)Voriconazole
Lomentospora(Scedosporium prolificans)Posaconazole
Lomentospora(Scedosporium prolificans)Isavuconazole
Lomentospora(Scedosporium prolificans)Caspofungin, Micafungin, or Anidulafungin
MucorAmphotericin B Formulations PosaconazoleItraconazole
MucorIsavuconazole
Paracoccidioides sppItraconazoleAmphotericin B Formulations
Paracoccidioides sppFluconazole
Paracoccidioides sppVoriconazole
Paracoccidioides sppPosaconazole
Paracoccidioides sppIsavuconazole
Penicillium sppItraconazoleVoriconazoleAmphotericin B Formulations
Penicillium sppPosaconazole
Penicillium sppIsavuconazole
Rhizopus sppAmphotericin B Formulations Posaconazole
Rhizopus sppIsavuconazole
Scedosporium apiospermumVoriconazoleItraconazole
Scedosporium apiospermumPosaconazoleCaspofungin, Micafungin, or Anidulafungin
Scedosporium apiospermumIsavuconazole
Sporothrix sppItraconazoleAmphotericin B Formulations
Sporothrix sppFluconazole
Sporothrix sppVoriconazole
Sporothrix sppPosaconazole
Sporothrix sppIsavuconazole
Trichosporon sppVoriconazoleFluconazole
Trichosporon sppItraconazole
Trichosporon sppPosaconazole
Trichosporon sppIsavuconazole

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